Learn more. suppository - a small plug of medication designed for insertion into the rectum or vagina where it melts medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease Based on WordNet 3.0, Farlex clipart collection. See more. Hydrophilic suppository bases also melt at body temperature, and … Suppository definition, a solid, conical mass of medicinal substance that melts upon insertion into the rectum or vagina. The first is the fat- or oil-type base, which must melt at body temperature to release its medication. Glycerinated Gelatin Polyethylene Glycols. What is the main advantage of a polyethylene glycol Suppository Base over Oleaginous Bases? [1350–1400; Middle English < Medieval Latin. an easily fusible medicated mass for introduction into the rectum, urethra, or vagina. So, the weight of the suppository base is 14 – 3=11 gm. https://www.thefreedictionary.com/Suppository+bases, A small plug of medication designed to melt at body temperature within a body cavity other than the mouth, especially the rectum or vagina. Definition Suppositories are solid single-dose preparations intended for rectal application. The shape, volume and consistency of suppositories are suitable for rectal application. 1. suppository - a small plug of medication designed for insertion into the rectum or vagina where it melts. Specifications for Suppository Bases 1 Origin & Chemical Composition:  A brief description of the composition of the base reveals the sours of the origin (natural or synthetic or modified natural products). . A suppository is a dosage form used to deliver medications by insertion into a body orifice where it dissolves or melts to exert local or systemic effects. a solid mass of medicinal substance that melts upon insertion into the rectum or vagina. The base of the suppository is a combination of coconut oil and cocoa butter, to which is added the desired combination of medicated oils, powdered herbs, and tinctures. A small, solid body shaped for ready introduction into one of the orifices of the body other than the oral cavity (e.g., rectum, urethra, vagina), made of a substance, usually medicated, that is solid at ordinary temperatures but melts at body temperature. Suppositories have a base made from substances like gelatin or cocoa butter that surrounds the drug. C. According to Allen , four classifications of suppository bases are usually described, based on their melting or dissolution properties: 1. Now the practical weight of the six suppositories is 14 gm and the total amount of the drug in all suppositories is equal to 6 * 500=3000 mg=3 g. Practical weight=14 gm. As the warmth of your body melts the … C. Emulsifying bases. B. Aqueous bases. Wecobee Witepsol. the suppository base and in anticipating drug release from that base. Such a hole is undesirable. Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. Suppository uses include asthma, allergies, and pain. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. Global fatty bases for suppositories market forecast is predicted tobe $6,565.1 million by 2027 at a healthy CAGR of 2.7%. A suppository, which is a general term for a solid dose of medicine that is inserted into the anus or the vagina, can contain different medications, from contraceptives to medication to kill off yeast infections. A tablet inserted into the anus or vagina that dissolves to administer a drug treatment or anesthesia. This contraction will produce a hole in the open end of the suppository. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. Europe’s fatty bases for suppositories market is expected to grow at a healthy CAGR of 3.2% by generating a revenue of $1,981.3 million, during the projected period. This is then poured into the mold, refrigerated to harden, cut into pieces the size of the patient's pinky finger, and inserted as needed. They are prepared by moulding or compression. •A lipophilic drug that is distributed in a fatty suppository base in low concentration has less tendency to escape to SUPPOSITORY BASE Lipid–Water Solubility •The lipid–water partition coefficient of a drug is an important consideration in the selection of the suppository base and in anticipating drug release from that base. These products are so formulated that after insertion, they will either melt or dissolve in … Suppositories have a base made from substances like gelatin or cocoa butter that surrounds the drug. Name the Oleaginous Suppository Bases that are Cocoa Butter substitutes. medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease. The selection of a suppository base is dependent upon a number of physicochemical variables, including the solubility characteristics of the drug. Hard fat suppository bases melt at approximately body temperature. Water soluble/water miscible bases are those containing glycerinated gelatin or the polyethylene glycol (PEG) polymers. A lipophilic drug that is distributed in a fatty suppository base in low concentration has less of a tendency to escape to the surrounding aqueous fluids than a hydrophilic drug in its saturation concentrations. Learn more. Suppository bases usually used are theobroma oil, glycerinated gelatin, hydrogenated vegetable oils, … Dictionary, Encyclopedia and Thesaurus - The Free Dictionary, the webmaster's page for free fun content, Suppress, Obscure, Secure, Reduce, and Assault, Suppress, Obscure, Secure, Reduce, Remove. weight is dependent upon the density of the drug, but mainly the density of the base - adult rectal suppositories are shaped as torpedo, bullet, or finger with a rectal dose weight about 2 grams when cocoa butter is used as a base - children rectal suppositories are more pencil shaped and about half the weight of the adult dose (1 gram) A suppository is a medication that is inserted into the rectum, vagina, or urethra to be broken down and absorbed by the body. Vaginal suppositories are one method of administering a drug to treat a specific disease or condition, or for contraceptive purposes. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. suppositories [L. suppositorium , something placed underneath] A semisolid substance for introduction into the rectum, vagina, or urethra, where it dissolves. suppository meaning: a small, solid pill containing a drug that is put inside the anus, where it dissolves easily. 67. Glycerinated Gelatin is a useful suppository base, particularly for vaginal suppositories. ( sŭ-poz'i-tō'rē ), A small solid preparation shaped for ready introduction into one of the orifices of the body other than the oral cavity (for example, rectum, urethra, vagina), made of a substance, usually medicated, which is solid at room temperatures but melts at body temperature. ry. So, by the addition of the drug , 1 gm of the suppository base is displaced. A. Oleaginous bases: Theobroma oil or cocoa butter was introduced as base in 1852 and has been one of the most widely used bases. As the warmth of your body melts the … Dictionary, Encyclopedia and Thesaurus - The Free Dictionary, the webmaster's page for free fun content, Suppress, Obscure, Secure, Reduce, and Assault, Suppress, Obscure, Secure, Reduce, Remove. Drug weight=3 gm. A medicinal substance that slowly dissolves after being inserted into the rectum (or other body cavity). There are three types of suppositories, each to insert into a different sections: Rectal suppositories into the rectum, vaginal suppositories into the vagina, and urethral suppositories into the urethra of a male. Suppository bases can be broadly divided into following categories- A. Oleaginous bases. See more. They come in different shapes and sizes, but they are usually narrowed at … Surfactant base. Suppository bases usually used are theobroma oil, glycerinated gelatin, hydrogenated vegetable oils, mixtures of polyethylene glycols of various molecular weights, and fatty acid esters of polyethylene glycol.